DuoBioX® Elite Series Benchtop Cell Culture Bioreactor price

Product Detail
Company Profile

1.Details

Duoning DuoBioX® Elite is a benchtop cell culture bioreactor system that supports dual culture modes. Users can quickly establish and develop cell culture processes ranging from 3 to 15 liters with this system, achieving process establishment, development, and optimization with a highly cost-effective investment. The DuoBioX® Elite system is ideal for the early development of cell culture processes in scientific research institutions or the biopharmaceutical industry.

2.Features

Design Concept

The Elite system fully complies with the technical performance requirements of bioreactors in the biopharmaceutical industry. The process software employs a user-friendly design language to facilitate easier operation. The system operates stably and reliably, occupies minimal space, and offers users options for both touch and mobile operation platforms.

Material Construction

The stainless-steel parts of the tank body that comes into contact with the liquid is constructed from SUS316L stainless steel and is electropolished to create an inert surface that is easy to clean. The glass tank body is made of high-quality tempered borosilicate glass, while the sealing materials consist of EPDM, silicone, and other substances that comply with FDA requirements. The non-liquid contact parts are made from high-quality SUS304 stainless steel.

3.Advantages

Various tank specifications are available, including 3L, 5L, 7L, 15L and more.
The software is powerful and capable of comprehensive control based on feedback, time, conditions, and script recipes, effectively meeting the user's stringent process requirements.
The operating system, developed on the WinCC industrial-grade architecture, complies with GMP and 21 CFR Part 11 regulations, making it suitable for use in industries such as pharmaceuticals and medical devices.
In addition to the fundamental parameters of dissolved oxygen (DO), pH, temperature, liquid level, and stirring control units, the system can accommodate up to three ventilation gas pathways: surface ventilation, macro sparger bottom ventilation, and micro sparger bottom ventilation. This flexibility allows users to implement diverse and adaptable ventilation strategies, effectively supporting high-density perfusion culture processes. Furthermore, the optimized exhaust gas cooling device significantly reduces the risk of exhaust gas filter blockage and is compatible with both fermentation and high-density cell culture applications.
The controller is designed with additional input interfaces to connect sensors, such as those for cell density, CO₂ levels, and weighing. It can also accommodate additional sensors in the control feedback system.

4.Specification

Elite 500mL	Elite 3L	Elite 7L	Elite 15L
Function	Cell culture type, 1 control 1 or 1 control 2 (optional)
Tank body
Working volume	400 mL	2 L	5 L	10 L
Total volume	500 mL	3.1 L	6.8 L	15 L
Min. working volume	100 mL	0.6 L	1.5 L	3.2 L
H-to-D ratio	2:1	1.9:1	2.2:1	2.0:1
Np value	1.5	1.5	1.5	1.5
Impeller	3 inclined blades 45°	3 inclined blades 45°	3 inclined blades 45°	3 inclined blades 45°
Impeller diameter	35 mm	45 mm	60 mm	75 mm
Vent pipe diameter	4 mm	6 mm	8 mm	8 mm
Macro sparger pore size	0.5 mm	1 mm	1 mm	1 mm
Number of macro spargers	3	5	7	7
Micro sparger pore size	None	Optional	Optional	Optional
Controller
pH sensor	Gel / 120	Gel / 225	Gel / 325	Gel / 325
DO sensor	243666-112/120 (Optical) H2	243666-132/225 (Optical) H2	243666-142/325 (Optical) H2	243666-142/325 (Optical) H2
CO₂ sensor	Optional	Optional	Optional	Optional
Overlay vent	Rotor flow meter	Rotor flow meter	Rotor flow meter	Rotor flow meter
MFC-Air	0~0.1 L	0~0.5 L	0~1 L	0~2 L
MFC-O₂	0~0.1 L	0~0.5 L	0~1 L	0~2 L
MFC-CO₂	0~0.1 L	0~0.5 L	0~0.5 L	0~1 L
MFC-N₂	Optional	Optional	Optional	Optional
MFC-O₂ micro sparger	0~0.1 Optional	0~0.1 Optional	0~0.5 Optional	0~1 Optional
Built-in peristaltic pump	4x built-in, viable speed	4x built-in, viable speed	4x built-in, viable speed	4x built-in, viable speed
Temperature control	Electric heating base 100w Cooling water solenoid valve	Electric heating blanket 400w Cooling water solenoid valve	Electric heating blanket 400w Cooling water solenoid valve	Electric heating blanket 400w Cooling water solenoid valve
Exhaust gas condensation	None	Semiconductor or water cooling	Semiconductor or water cooling	Semiconductor or water cooling
Weighting	Optional	Optional	Optional	Optional
Control software (needs to be installed on the user's computer)
21 CFR Part 11	Yes	Yes	Yes	Yes
Data records	Yes	Yes	Yes	Yes
User authorization management	4 levels	4 levels	4 levels	4 levels
Utility requirements
Air source	Air, O₂, CO₂	Air, O₂, CO₂	Air, O₂, CO₂	Air, O₂, CO₂
Air source pressure	0.2-0.3 MPa	0.2-0.3 MPa	0.2-0.3 MPa	0.2-0.3 MPa
Control cabinet power supply	220 v 50 Hz	220 v 50 Hz	220 v 50 Hz	220 v 50 Hz
Power socket	10A three-hole	10A three-hole	10A three-hole	10A three-hole
Control cabinet dimension	DepthWidthHeight 520350618 mm	DepthWidthHeight 520350618 mm	DepthWidthHeight 520350618 mm	DepthWidthHeight 520350618 mm
External dimensions of a single tank (w/o exhaust condenser)	HeightDiameter 357100 mm	HeightDiameter 410210 mm	HeightDiameter 520250 mm	HeightDiameter 620280 mm
Control cabinet net weight	35 kg	35 kg	35 kg	35 kg
Tank net weight	2 kg	8 kg	11 kg	15 kg

Duoning Biotech is a leading one-stop bioprocess solutions provider from China, committed to offering products and services required for the discovery, development and commercialization production of biologics, including reagents, consumables, instruments, equipment, and services. Leveraging our integrated bioprocess system, we empower our customers to achieve effective, reliable, lower-cost and higher-quality biologics manufacturing processes.