DuoBioX® Pro Single-use Bioreactor price

Product Detail
Company Profile

1.Details

DuoBioX

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Pro single-use bioreactor adopts bottom-stirring tank design, which can realize linear scale-up from 50L to 2,000L. Combined with 3D disposable cell culture bags independently developed and manufactured by Duoning, there bioreactors features good biocompatibility, together with flexible connection design, they can meet all requirements of complex upstream processes; their unique combination design of stirring and ventilation, not only reduce shear but also ensure excellent mass transfer and mixing performance, thus achieving good consistency during scaling-up. The DuoBioX

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Pro single-use bioreactors can be widely used in various stages from process development to GMP production of biopharmaceuticals.

2.Features

The cell culture bag features good biocompatibility, extremely low extractables and leachable, and ensures the safety of the product. All materials in contact with the product have passed relevant validation requirements of CFDA for single-use system and meet USP standards.
The system is designed with Siemens PLC+WinCC system, can be connected to SCADA data management system, all data can be recorded and exported, and supports audit trail, while complies with 21CFR Part 11 regulations.
The system integrates optical dissolved oxygen sensor with DO resolution of 0.1% and control accuracy of ±2%, the pH resolution is 0.01 with control accuracy of ±0.02; and temperature resolution is 0.1°C with control accuracy of ±0.5°C; the weighing accuracy is ±3‰ with pressure accuracy ±of 2%.
The default configuration provides 3 channels of gas supply: macro-sparge bottom gas supply (0.05 vvm oxygen, 0.05 vvm air, 0.025 vvm carbon dioxide), micro-sparge bottom gas supply (0.025 vvm oxygen), overlay gas supply (0.05 vvm oxygen, 0.05 vvm air). All use Swiss Vogtlin or German Bürkert mass flowmeter.
1-2 way exhaust heating as standard (depending on the model of the culture bag); magnetic coupling stirring device with inclined angle at the bottom, speed 0-300 rpm, temperature control range 20-50 ℃.
Mettler-Toledo high precision load cell unit.

Hardware: The main spare parts are from industry leading suppliers, thus improve the product quality and stability of the hardware and reduce failure rate
Software: With rich experience in bioreactor development and careful consideration of characteristics of various cell culture processes, Duoning has built a mature control software system.
Service: Professional technical service team, after-sales training and services of bioreactors will be provided by experienced engineers, until end-users master all required skills.
After-sales: Relying on the strong after-sales service team of Duoning, we have set up offices in various regions, and can respond immediately to technical and after-sales problems.

4.Specification

Tank and I/O Cabinet

Duoning Biotech is a leading one-stop bioprocess solutions provider from China, committed to offering products and services required for the discovery, development and commercialization production of biologics, including reagents, consumables, instruments, equipment, and services. Leveraging our integrated bioprocess system, we empower our customers to achieve effective, reliable, lower-cost and higher-quality biologics manufacturing processes.