DuoWave® Wave-type Single-use Bioreactor

The DuoWave® wave-type bioreactor features a unique mixing mechanism that provides a gentler growth environment for cells. Its newly designed process control software offers rich functionality with a clean and intuitive interface, making it easy for users to operate and master. The DuoWave® system supports a working volume range of 100 mL to 25 L, making it suitable for rapid expansion of various cell types, seed preparation, process development, and quick laboratory-scale sample production.

Applications:

Depending on the mode of operation, DuoWave® wave-type bioreactors can be applied to

Ÿ  Seed Expansion

Ÿ  Fed-Batch

Ÿ  Perfusion

Ÿ  Microcarrier-based Culture

Depending on different applications, DuoWave® wave-type bioreactors can be applied to

Ÿ  Antibody and recombinant proteins

Ÿ  Vaccine

Ÿ  Gene therapy

Ÿ  Cell therapy

Ÿ  Other biologics or macro molecular

Key Features

The DuoWave® wave-type bioreactor adopts a brand-new modular design, consisting of four modules: base unit, tray, I/O module, and server. It enables quick installation, easy operation, and space-saving integration.

Ÿ   The base module provides temperature control, rocking agitation, weighing, and exhaust gas heating functions. The tray features a quick-connect design for fast replacement.

Ÿ   The tray is available in 20 L and 50 L specifications and adopts a dual-zone heating plate design, allowing independent temperature control of two cell culture bags.

Ÿ   The I/O module integrates single-use optical pH and DO sensors, gas mixing, and high-precision peristaltic pump functions, enabling easy implementation of process parameter feedback control.

Ÿ   The server module includes DuoWave® control software and a computer, allowing users to perform process control, audit trail management, data recording, four-level user access control, and batch report generation. The DuoWave® wave-type bioreactor system complies with GMP and 21 CFR Part 11 regulatory requirements.

3.Advantages

Mass Transfer and Mixing Performance

DuoWave® wave bioreactor system not only has excellent mass transfer and mixing performance but also brings extremely low shear force and suitable growth environment for cell culture due to its unique non-sparging aeration and non-stirring design.

Configuration