Stainless Steel Suspension Cell Culture Bioreactor

These systems can be used for suspension culture, microcarrier culture for monoclonal antibody, vaccine or protein-based therapeutics production, to achieve multiple use in one tank.

Suspension and microcarrier culture using propulsion impeller or lifting impeller, low shear force, short mixing time, good mixing effect

Deep microbubble direct air supply/bubble-free air supply device provide good oxygen transfer, meets the requirements of high-density cell culture, and reduces the damage to cells

Using jacket and tank dual temperature PID control, temperature control is stable and accurate

Sterilization-in-place sampling/sampling valve group to ensure safe, reliable and convenient operation

Air intake/exhaust filter sterilization can be carried out independently to meet the requirements of filter replacement during the culture process

CO₂/O₂/AIR flow rate adopts thermal mass flow controller, to realize the automatic feedback control of gas flow rate

Dissolved oxygen control can adopt AIR/O₂ or AIR/O₂/N₂ mode. The DO control adopts unique PID control logic for stable and accurate control

Deep sparger and overlay air supply adopt different control methods in sterilization process, to ensure thorough sterilization and no dead end

Deep sparger uses a combination of hardware and software, effectively eliminate culture fluid reflux

PH control adopts time judgment to avoid the simultaneous addition of CO₂ and base

Peristaltic pump control allows external mobile peristaltic pump, easy to replace

Pipeline and frame adopt open design, easy to use and maintain

Pipeline adopts 3A standard, comply with GMP and BPE requirements

Connection seal of the mixing impeller in the tank effectively avoids dead end and is easy to clean

Pipeline construction is carried out in cleanroom to ensure welding quality

Material inlet and tank bottom valves can be sterilized separately

All the pipelines and tee connections on the tank body meet 3D requirements

Dual mechanical seal, sterilization-in-place; or bottom magnetic stirring

The control system adopts PLC control

Servo motor, large torque, realizes stable and reliable work

Powerful software functions, such as parameter setting, display control, test parameter, curve analysis, data storage, and output printing

System adopts electronic signature, which meets the requirements of GMP audit