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Bioreactors
- Sanitary diaphragm valves
- Product Detail
- Company Profile
- Sanitary diaphragm valves
Sanitary diaphragm valves are valves suitable for fluid related industries such as pharmaceuticals, biology, dairy products, beverages, chemicals, cosmetics, food, electronics, etc.
Its design aims to meet the requirements of no dead corners, no leaks, easy cleaning, easy maintenance, etc., in order to reduce the operating costs of enterprises. All membranes used comply with FDA/USP classification and TSE/ADI standards,
The film complies with the safety standards set by authoritative agencies such as FDA and UPS for the pharmaceutical and food industries. Its structure usually separates the valve body and valve cover with a diaphragm, so that the upper parts such as the valve stem are not corroded by the medium, achieving a leak free seal.
The flow channel adopts streamlined or Y-shaped design to reduce resistance, and the valve body is precision polished to meet the requirements of sterility and no dead corners.
The nominal pressure range is usually between 0.6MPa and 1.6MPa, and the applicable temperature range can reach -30 ℃ to 150 ℃.
The valve body material is mostly stainless steel (such as SUS304, SUS316L), and the connection methods include quick installation, welding, flanges, etc.
The product is widely used in systems with high sterile requirements such as biopharmaceuticals and injection water. Typical applications include fermentation tanks, preparation tanks, filling machines, sterile filters, etc
Water production equipment, PW/WIFI transportation and distribution, sterile fluid transportation and CIP (online cleaning), SIP (online sterilization), etc
1. Main parameters
Valve body: 316L stainless steel, inner cavity mirror/electrolytic polishing (Ra ≤ 0.8 μ m)
Diaphragm: EPDM, silicone, FKM, PTFE coated (food/pharmaceutical grade)
Valve stem/actuator: manual (handwheel), pneumatic, electric
Valve seat: Smooth weir type/straight through structure, no dead corners
2. Working principle
Close: Valve stem pressed down → Diaphragm bent tightly against valve seat → Cut off flow channel
Open: Valve stem up → Diaphragm rebound → Smooth flow channel
Key: The diaphragm completely isolates the medium from the upper drive mechanism, with no packing or leakage
3. Product advantages
（1）. Zero dead corners, no residue
Smooth and continuous flow channel, no grooves or threads, CIP/SIP easy to clean and sterilize
（2）. Absolute clean seal
The diaphragm is the only sealing component, without lubricant or metal contact contamination
Completely isolated inside and outside to prevent cross contamination
（3）. Material compliance
Valve body: 316L
Diaphragm: Compliant with FDA, USP Class VI, 3-A, EHEDG
（4）. Zero leakage and easy maintenance
No stuffing box to prevent external leakage; Diaphragm can be replaced separately, easy to maintain
4. Driving mode
• Manual: Handwheel/knob, small caliber, manual working condition
Pneumatic (most commonly used): normally closed/normally open/pneumatic type, equipped with solenoid valve, feedback, locator
• Electric: automation, remote control
5. Connection method
Quick installation (clamp/Tri Clamp): the most commonly used, quick to disassemble and easy to clean
• Welding: butt welding/socket welding, permanent sealing, no dead corners
• Sanitary flange/thread
6. Typical Applications
• Pharmaceutical/Biological: Injection Water (WFI), Ingredients, Fermentation, Chromatography, Aseptic Filling CIP/SIP
• Food and beverage: dairy products, beer, juice, soy sauce, vinegar, pure water
• Semiconductors/Electronics: Ultra pure water, chemicals, photoresist
• Cosmetics/Fine Chemicals: High cleanliness raw material transportation
7. Product selection
Caliber: DN6 to DN100
Valve body material: 316L standard
Diaphragm material: PTFE, EPDM, silicone, FKM
Pressure: 0-1Mpa
Temperature: -20 ℃~150 ℃
Standard: 3A, ASME BPE
Product Selection
Dimensions of manual and pneumatic actuators
| No | Model（DN） | φE | H | φE1 | H1 |
| 1 | DN6-15 | φ35 | 62 | φ50 | 96 |
| 2 | DN15-20 | φ65 | 83 | φ75 | 136 |
| 3 | DN20-25 | φ90 | 106 | φ88 | 150 |
| 4 | DN32-45 | φ110 | 125 | φ100 | 178 |
| 5 | DN50-57 | φ125 | 148 | φ112 | 225 |
| 6 | DN65-80 | φ145 | 186 | φ138 | 306 |
| 7 | DN89 | φ180 | 205 | φ200 | 354 |
| 8 | DN100 | φ180 | 256 | φ250 | 395 |
If you have any questions, please feel free to call for consultation,
pangjun@costones.com
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Suzhou COSTONES Instruments Co., Ltd. (COSTONES) is an instrument company focusing
on separation and purification. It is an equipment supplier and service provider
for biopharmaceutical, cell therapy and gene testing. It is committed to providing
users with industry-leading technical support and services.
The company has a perfect service system and executive power. It interprets the
user experience from the four aspects of technical communication, scheme design,
technical support and after-sales service, and tries to achieve seamless connection
in every link until it is recognized by customers.
For a long time, we have maintained good cooperative relations with domestic and
foreign suppliers. The main products include protein purification system,
compressible chromatographic column, ultrafiltration system, chromatographic
ultrafiltration accessories, etc., and provide maintenance services and customized
product services;
At present, Suzhou quarrying has provided high-quality services for
biopharmaceutical, cell therapy, research institutes and scientific research users.
It has carried out in-depth cooperation with customers and become a reliable partner
for customers to achieve win-win results.
We take quality first as the standard, quickly respond to customer needs, help
customers solve problems, improve efficiency, and take improving core
competitiveness for customers as our service tenet. We are willing to realize our
own value while creating value for customers and society through our unremitting
efforts.
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