AccuSift provides high‑performance aflatoxin B1 competitive assay pairings, characterized by exceptional batch‑to‑batch consistency and optimized for IVD kit development (Lateral Flow, Chemiluminescence, ELISA, POCT). These pairings offer high affinity and specificity, facilitating rapid detection.
Aflatoxins are difuranocoumarin‑derived mycotoxins produced by certain strains of Aspergillus flavusand Aspergillus parasiticus. There are approximately 20 derivatives, designated B1, B2, G1, G2, M1, M2, GM, P1, Q1, aflatoxicol, etc. Among them, aflatoxin B1 is the most toxic and the strongest carcinogen. When animals consume feed contaminated with aflatoxins, trace amounts of the toxins can be detected in the liver, kidneys, muscles, blood, milk, and eggs. Aflatoxins and their producing fungi are widely distributed in nature, with some strains producing more than one type, and some A. flavusstrains produce no aflatoxins. Aflatoxins primarily contaminate grains, oils, and their products, but can also affect various plant‑ and animal‑based foods. Toxigenic Aspergillusreadily colonize and produce toxins in cereals and oilseeds with high moisture content (below 12% moisture, they cannot proliferate) and their processed by‑products, causing spoilage. Human poisoning occurs through ingestion of such contaminated foods or by‑products, with toxins absorbed via the digestive tract.
On October 27, 2017, the World Health Organization’s International Agency for Research on Cancer (IARC) listed aflatoxins as Group 1 carcinogens in its preliminary compilation.
Performance Characteristics:
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Sensitivity: ELISA IC50: 0.03 ppb; Colloidal Gold: 0.1 ppb
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Cross‑Reactivity: B2 < 20%; G1, G2 < 5%
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Purity: ≥ 90%
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