β-lactams receptor Competitive Antibody Pair

AccuSift provides high-performance β-lactam receptor competitive assay pairings, characterized by exceptional batch-to-batch consistency and optimized for IVD kit development (Lateral Flow, Chemiluminescence, ELISA, POCT). These pairings offer high affinity and specificity, facilitating rapid detection.

The β-lactam receptor (β-lactams receptor) is a class of specialized proteins on the bacterial cell membrane, belonging to the Penicillin-Binding Proteins (PBPs) family. It serves as the target for β-lactam antibiotics. Its core function is to recognize and bind β-lactam antibiotics (e.g., penicillins, cephalosporins), disrupting the synthesis of bacterial cell wall peptidoglycan, ultimately leading to bacterial lysis and death.

Product SE123 Performance Characteristics:

•Sensitivity: ELISA IC50: 0.5 ppb; Colloidal Gold Visual Cut-off: 5 ppb

•Cross-Reactivity:

1.Penicillin G: IC50 0.1 ppb; Colloidal Gold 0.5–1 ppb

2.Ampicillin: IC50 0.2 ppb; Colloidal Gold 1–2 ppb

3.Amoxicillin: IC50 0.2 ppb; Colloidal Gold 1–2 ppb

4.Oxacillin: IC50 0.3 ppb; Colloidal Gold 2–3 ppb

5.Cloxacillin: IC50 0.3 ppb; Colloidal Gold 3–4 ppb

6.Dicloxacillin: IC50 0.3 ppb; Colloidal Gold 2–3 ppb

7.Nafcillin: IC50 0.5 ppb; Colloidal Gold 5–10 ppb

8.Cefacetrile: IC50 1 ppb; Colloidal Gold 10–15 ppb

9.Cefoperazone: IC50 0.5 ppb; Colloidal Gold 4–5 ppb

10.Ceftriaxone: IC50 3 ppb; Colloidal Gold 20–30 ppb

11.Ceftiofur: IC50 4 ppb; Colloidal Gold 30–40 ppb

12.Cefalonium: IC50 0.2 ppb; Colloidal Gold 1–3 ppb

13.Cefquinome: IC50 1 ppb; Colloidal Gold 10–15 ppb

14.Cephapirin: IC50 1 ppb; Colloidal Gold 10–15 ppb

15.Cefalexin: IC50 50 ppb; Colloidal Gold 500 ppb

Product SR734 Performance Characteristics:

•Sensitivity: ELISA IC50: 0.5 ppb; Colloidal Gold Visual Cut-off: 5 ppb

•Cross-Reactivity (IC50, ppb; CR%):

1.Ampicillin: IC50 2.0; CR 100.00%

2.Benzylpenicillin: IC50 1.0; CR 200.00%

3.Cloxacillin: IC50 2.0; CR 100.00%

4.Dicloxacillin: IC50 2.0; CR 100.00%

5.Cefoperazone: IC50 2.0; CR 100.00%

6.Cefalonium: IC50 2.0; CR 100.00%

7.Cefamandole: IC50 2.0; CR 100.00%

8.Cefepime: IC50 2.0; CR 100.00%

9.Penicillin V potassium: IC50 2.5; CR 80.00%

10.Amoxicillin: IC50 4.0; CR 50.00%

11.Procaine penicillin: IC50 5.0; CR 40.00%

12.Cefathiamidine: IC50 5.0; CR 40.00%

13.Cefapirin: IC50 5.0; CR 40.00%

14.Oxacillin: IC50 5.0; CR 40.00%

15.Cefquinome: IC50 5.0; CR 40.00%

16.Moxalactam: IC50 5.0; CR 40.00%

17.Cefalotin: IC50 5.0; CR 40.00%

18.Cephalothin: IC50 5.0; CR 40.00%

19.Meropenem: IC50 5.0; CR 40.00%

20.Nafcillin: IC50 10.0; CR 20.00%

21.Ertapenem: IC50 10.0; CR 20.00%

22.Cefotaxime: IC50 20.0; CR 10.00%

23.Cefuroxime: IC50 20.0; CR 10.00%

24.Ceftriaxone: IC50 20.0; CR 10.00%

25.Cefazolin: IC50 20.0; CR 10.00%

26.Cefaclor: IC50 25.0; CR 8.00%

27.Cefixime: IC50 25.0; CR 8.00%

28.Cefoxitin: IC50 25.0; CR 8.00%

29.Cefacetrile: IC50 25.0; CR 8.00%

30.Ceftiofur: IC50 25.0; CR 8.00%

31.Cefalexin: IC50 100.0; CR 2.00%

32.Cefadroxil: IC50 100.0; CR 2.00%

33.Cephradine: IC50 500.0; CR 0.40%

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