The Virus Platform provides packaging services for a variety of viral types including retrovirus,lentivirus, adenovirus, adeno-associated virus. The viral titer and purity are guaranteed for effective infection for both cultured cells and tissues. The lead time for virus packaging ranges from 1 month to 3 months.
Adeno-associated virus (AAV) is a small virus which infects humans and some other primate species. AAV is not currently known to cause disease. Moreover, virus infection causes a very mild immune response. AAV can infect both dividing and non-dividing cells These features make AAV a very attractive candidate for creating viral vectors for gene therapy, and for the creation of isogenic human disease models. Recent human clinical trials using AAV for gene therapy in the retina have shown promise. Different AAV serotypes have demonstrated patterns for the target genes in terms of expression time and host selectivity. The Biowit virus platform provides a variety of AAV2 serotypes including AAV2/1, AAV2/2, AAV2/3, AAV2/4, AAV2/5, AAV2/6, AAV2/7, AAV2/8 and AAV2/9. The titer of packaged AAV ranges from 1x1011-1x 1012 vg/ml.
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