HB-EGF Protein, Rat,UA BIOSCIENCE_specification/price/image

Product Detail
Company Profile

Product Specification

Species	Rat
Accession	Q06175
Amino Acid Sequence	Asp63-Leu148
Expression System	E.coli
Molecular Weight	10 kDa (Reducing)
Purity	>95% by SDS-PAGE.
Endotoxin	<0.1EU/μg
Conjugation	Unconjugated
Tag	No Tag
Physical Appearance	Lyophilized Powder
Storage Buffer	PBS, pH7.4
Reconstitution	Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.
Stability & Storage	·12 months from date of receipt, lyophilized powder stored at -20 to -80℃. ·3 months, -20 to -80℃ under sterile conditions after reconstitution. ·1 week, 2 to 8℃ under sterile conditions after reconstitution. ·Please avoid repeated freeze-thaw cycles.
Reference	Diabetes. 2020 Mar;69(3):369-380. Gastroenterology. 2003 Apr;124(4):1020-36.

Background

Heparin-Binding Epidermal Growth Factor-like Growth Factor (HB-EGF) is a multifunctional growth factor that plays a crucial role in various cellular processes, including proliferation, differentiation, and tissue repair. In rats, HB-EGF has been extensively studied for its role in pancreatic beta-cell proliferation and glucose homeostasis.
HB-EGF has been studied extensively in rat models of diabetes to understand its role in beta-cell regeneration and proliferation. For instance, HB-EGF has been shown to promote beta-cell proliferation in rats with partial pancreatectomy. This suggests that HB-EGF could be a potential therapeutic target for enhancing beta-cell mass and improving glucose homeostasis in diabetes.

AntBio is a biotechnology group company dedicated to serving life sciences, aiming to help scientists accelerate research and improve work efficiency. AntBio provides comprehensive and high-quality reagent tools for basic research, drug development, and diagnosis, including research grade antibodies, proteins, biochemical reagents, and assay kits. These research tools are widely used in different segments of life science research. The group company currently consists of three brands, Absin, Starter-Bio and UA-Bio.