TACI/CD267/TNFRSF13B His Tag Protein, Human,UA BIOSCIENCE_specification/price/image

Product Detail
Company Profile

Product Specification

Species	Human
Synonyms	CVID; CVID2; FLJ39942; MGC133214; ACIMGC39952; TNFRSF13B
Accession	O14836-1
Amino Acid Sequence	Ser2-Thr166 with His Tag at the C-terminus
Expression System	HEK293
Molecular Weight	19-22kDa (Reducing)
Purity	＞95% by SDS-PAGE & RP-HPLC
Endotoxin	<0.1EU/μg
Conjugation	Unconjugated
Tag	His Tag
Physical Appearance	Lyophilized Powder
Storage Buffer	PBS, PH7.4,5% trehalose
Reconstitution	Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.
Stability & Storage	· 12 months from date of receipt, lyophilized powder stored at -20 to -80℃. · 3 months, -20 to -80℃ under sterile conditions after reconstitution. · 1 week, 2 to 8℃ under sterile conditions after reconstitution. · Please avoid repeated freeze-thaw cycles.
Reference	von Bulow, G.U. et al. (1997) Science, 278:138. Marsters, S.A. et al. (2000) Curr. Biol. 10:785.

Background

TACI (Transmembrane activator and CAML interactor) is a type III transmembrane protein and a member of the TNF receptor superfamily. It consists of an extracellular domain containing two cysteine-rich regions, a transmembrane domain, and an intracellular domain. TACI shares high homology with BCMA and binds to APRIL and BAFF, key ligands involved in immune regulation. Expressed on B cells and activated T cells, TACI plays a crucial role in B cell development and function. Its interactions with APRIL and BAFF suggest involvement in immune signaling pathways, making it a potential target for immunotherapy.

AntBio is a biotechnology group company dedicated to serving life sciences, aiming to help scientists accelerate research and improve work efficiency. AntBio provides comprehensive and high-quality reagent tools for basic research, drug development, and diagnosis, including research grade antibodies, proteins, biochemical reagents, and assay kits. These research tools are widely used in different segments of life science research. The group company currently consists of three brands, Absin, Starter-Bio and UA-Bio.