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ZNRF3 His Tag Protein, Human
ZNRF3 His Tag Protein, Human
Place of Origin:
Singapore
Brand:
UA BIOSCIENCE
Model:
UA011107-25μg
Price:
36
Hits:
Updated:
9/1/2025
  • Product Detail
  • Company Profile

    Product Specification


    SpeciesHuman
    SynonymsZNRF3, Zinc,RING finger protein 3, RING-type E3 ubiquitin transferase ZNRF3, RING finger protein 203, KIAA1133, RNF203
    AccessionQ9ULT6-1
    Amino Acid Sequence

    Lys56-Met219 with His Tag at C-Terminus

    Expression SystemHEK293
    Molecular Weight

    22-23kDa (Reducing)

    Purity>95% by SDS-PAGE
    ConjugationUnconjugated
    TagHis Tag
    Physical AppearanceLyophilized Powder
    Storage BufferPBS, PH7.4, 5% trehalose
    Reconstitution

    Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.

    Stability & Storage

    · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃. 
    · 3 months, -20 to -80℃ under sterile conditions after reconstitution.
    · 1 week, 2 to 8℃ under sterile conditions after reconstitution.  
    · Please avoid repeated freeze-thaw cycles.

    Reference

    Fu S, Qian M, Yuan Z, Su S, Ma F, Li F, Xu Z. A new perspective on selenium's impact on renal function: European population-based analysis of plasma proteome-mediated Mendelian randomization study. Front Endocrinol (Lausanne). 2024 Sep 12;15:1410463.

    Background

    The transmembrane E3 ubiquitin ligase, Zinc and Ring Finger 3 (ZNRF3), serves as a negative feedback regulator of Wnt signaling. ZNRF3 is associated with the Wnt receptor complex and inhibits Wnt signaling by promoting the turnover of Frizzled and LRP6. Additionally, ZNRF3 functions as a tumor suppressor in the intestinal stem cell compartment by inhibiting the Wnt signaling pathway.

    bio-equip.cn
    AntBio is a biotechnology group company dedicated to serving life sciences, aiming to help scientists accelerate research and improve work efficiency. AntBio provides comprehensive and high-quality reagent tools for basic research, drug development, and diagnosis, including research grade antibodies, proteins, biochemical reagents, and assay kits. These research tools are widely used in different segments of life science research. The group company currently consists of three brands, Absin, Starter-Bio and UA-Bio.
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