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CD24 mFc Chimera Protein, Human
CD24 mFc Chimera Protein, Human
Place of Origin:
Singapore
Brand:
UA BIOSCIENCE
Model:
UA011100-25μg
Price:
256
Hits:
10 
Updated:
9/1/2025
  • Product Detail
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    Product Specification


    SpeciesHuman
    SynonymsSignal transducer CD24; Ly-52; HAS; Nectadrin; R13-Ag; CD24; CD24A
    AccessionP25063-1
    Amino Acid Sequence

    Ser27-Gly59 with Mouse IgG2a Fc at C-Terminus

    Expression SystemHEK293
    Molecular Weight40-55kDa (Reducing)
    Purity>95% by SDS-PAGE
    ConjugationUnconjugated
    TagMouse IgG2a Fc
    Physical AppearanceLyophilized Powder
    Storage BufferPBS, PH7.4, 5% trehalose
    ReconstitutionReconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.
    Stability & Storage· 12 months from date of receipt, lyophilized powder stored at -20 to -80℃.
    · 3 months, -20 to -80℃ under sterile conditions after reconstitution.
    · 1 week, 2 to 8℃ under sterile conditions after reconstitution.
    · Please avoid repeated freeze-thaw cycles.
    Reference

    1. Ho IC, et al. (2009) GATA3 and the T-cell lineage: essential functions before and after T-helper-2-cell differentiation. Nat Rev Immunol. 9 (2): 125-35. 2.Matesanz-Isabel J, et al. (2011) New B-cell CD molecules. Immunology Letters.134 (2): 104-12.

    Background

    Cluster of Differentiation 24 (CD24) is a mucin-type glycoprotein linked to the cell membrane via glycosylphosphatidylinositol (GPI). It is expressed on the surface of B-cells. Elevated levels of CD24 expression have been observed in various epithelial cancers, including ovarian, breast, non-small cell lung, prostate, and pancreatic cancers. CD24 plays a role in molecular adhesion and the spread of metastatic tumors, and it serves as a normal receptor for P-selectin. The CD24/P-selectin interaction may be significant in the dissemination of tumor cells by facilitating their interaction with platelets and endothelial cells. Furthermore, CD24 has been considered a potential tumor marker.

    bio-equip.cn
    AntBio is a biotechnology group company dedicated to serving life sciences, aiming to help scientists accelerate research and improve work efficiency. AntBio provides comprehensive and high-quality reagent tools for basic research, drug development, and diagnosis, including research grade antibodies, proteins, biochemical reagents, and assay kits. These research tools are widely used in different segments of life science research. The group company currently consists of three brands, Absin, Starter-Bio and UA-Bio.
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