Epiregulin Protein, Human,UA BIOSCIENCE_specification/price/image

Product Detail
Company Profile

Product Specification

Species	Human
Synonyms	Epiregulin; EPR
Accession	O14944
Amino Acid Sequence	Val63-Leu108, with N terminal hIgG1 Fc
Expression System	HEK293
Molecular Weight	33 kDa (Reducing)
Purity	>95% by SDS-PAGE and HPLC.
Conjugation	Unconjugated
Tag	Human IgG1 Fc
Physical Appearance	Lyophilized Powder
Storage Buffer	PBS, pH7.4
Reconstitution	Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.
Stability & Storage	· 12 months from date of receipt, lyophilized powder stored at -20 to -80℃. · 3 months, -20 to -80℃ under sterile conditions after reconstitution. · 1 week, 2 to 8℃ under sterile conditions after reconstitution. · Please avoid repeated freeze-thaw cycles.
Reference	Gene.2006 Jan 17;366(1):2-16. Epub 2005 Dec 27.

Background

Epiregulin is a member of the epidermal growth factor (EGF) family of proteins that plays a crucial role in cell signaling and regulation. It acts as a ligand for the epidermal growth factor receptor (EGFR) and is involved in various cellular processes, including cell proliferation, survival, migration, and differentiation. Epiregulin exerts its cellular activities by binding to EGFR and activating downstream signaling pathways, such as the MAPK/ERK and PI3K/Akt pathways, which regulate gene expression and cellular responses. The dysregulation of epiregulin signaling has been implicated in cancer development, metastasis, and resistance to therapy, highlighting its importance in cellular homeostasis and disease progression.

AntBio is a biotechnology group company dedicated to serving life sciences, aiming to help scientists accelerate research and improve work efficiency. AntBio provides comprehensive and high-quality reagent tools for basic research, drug development, and diagnosis, including research grade antibodies, proteins, biochemical reagents, and assay kits. These research tools are widely used in different segments of life science research. The group company currently consists of three brands, Absin, Starter-Bio and UA-Bio.