NT-proBNP, Human,Starter_specification/price/image

Product Detail
Company Profile

Product Specification

Species	Human
Synonyms	NT-proBNP;BNF, BNP, brain type natriuretic peptide, Gamma-brain natriuretic peptide, natriuretic peptide B, natriuretic peptide precursor B, natriuretic peptides B, natriuretic protein, NPPB
Accession	P16860
Amino Acid Sequence	HHHHHHHPLG SPGSASDLET SGLQEQRNHL QGKLSELQVE QTSLEPLQES PRPTGVWKSR EVATEGIRGH RKMVLYTLRA PR
Expression System	E.coli
Molecular Weight	9.2 kDa
Purity	＞95%, by SDS-PAGE under reducing conditions
Endotoxin	<0.2EU/μg
Conjugation	Unconjugated
Tag	His Tag
Physical Appearance	Lyophilized Powder
Storage Buffer	PBS (pH7.2)
Reconstitution	Reconstitute at less than 1 mg/mL according to the size in ultrapure water after rapid centrifugation .
Stability & Storage	· 12 months from date of receipt, -20 to -70 °C as supplied. · 6 months, -20 to -70 °C under sterile conditions after reconstitution. · 1 week, 2 to 8 °C under sterile conditions after reconstitution. · Please avoid repeated freeze-thaw cycles.

Background

The N-terminal fragment of pro-brain natriuretic peptide (N-terminal-prohormone Brain Natriuretic Peptide, NT-proBNP), whose molecular weight is 8.5kDa, belongs to the natriuretic peptide family protein, also known as type B brain natriuretic peptide, which has the functions of natriuretic, diuretic, vasodilation and so on. NT-proBNP is mainly synthesized and secreted by ventricular myocytes. Cardiac dysfunction such as high ventricular load and increased wall tension are the main conditions for stimulating NT-proBNP secretion, and the intensity of these stimulating factors is proportional to the content of NT-proBNP. Therefore, NT-proBNP can reflect the changes of ventricular function with strong specificity and high sensitivity, is a very important clinical marker of heart failure, and plays an irreplaceable role in early heart failure screening, prognosis evaluation and so on.

AntBio is a biotechnology group company dedicated to serving life sciences, aiming to help scientists accelerate research and improve work efficiency. AntBio provides comprehensive and high-quality reagent tools for basic research, drug development, and diagnosis, including research grade antibodies, proteins, biochemical reagents, and assay kits. These research tools are widely used in different segments of life science research. The group company currently consists of three brands, Absin, Starter-Bio and UA-Bio.