Rab11 is a member of the Rab family of small GTPases that plays a pivotal role in membrane trafficking, particularly in the recycling of membrane components from endosomes back to the plasma membrane. It is predominantly found in recycling endosomes and is crucial for the transport of vesicles from these endosomes to the cell surface, facilitating the reuse of receptors and membrane proteins. Its function has been well-defined in the recycling pathway, but its role in early endosomes is less understood. Recent studies have also implicated Rab11 in the balance of the endosome-lysosome pathway, suggesting its broader impact on cellular homeostasis. Overall, Rab11 is a key regulator in the maintenance of cellular membrane dynamics and the control of intracellular trafficking routes.
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