Introduction
Bovine Pregnancy-Associated Glycoproteins (bPAGs) are aspartic peptidases primarily secreted by the binucleate trophoblast cells of the ruminant placenta. Their presence in maternal blood serum serves as a highly specific biomarker for pregnancy detection and monitoring in cattle.
Key Features
High Specificity: Specifically targets epitopes unique to bovine PAG isoforms, ensuring minimal cross-reactivity with non-target proteins.
High Affinity: Demonstrates strong binding affinity for bPAGs, enabling sensitive detection in complex biological samples (e.g., serum, plasma, milk).
Validated Performance: Rigorously tested for use in ELISA, Western Blotting, Immunohistochemistry (placental tissue), and rapid diagnostic test formats.
Reliable & Reproducible: Manufactured under stringent quality control to ensure batch-to-batch consistency.
Intended Use
This Anti-Bovine PAG Antibody is intended for research use only (RUO) and in vitro diagnostic (IVD) applications for the detection and quantification of bovine Pregnancy-Associated Glycoproteins. Its primary applications include:
Early Pregnancy Diagnosis: Detection of bPAGs in maternal serum or milk as early as 28 days post-breeding.
Pregnancy Confirmation & Monitoring: Quantitative assessment of bPAG levels throughout gestation.
Placental Function Studies: Investigation of trophoblast cell biology and placental development in cattle.
Development of Diagnostic Kits: Essential component for ELISA kits, lateral flow immunoassays (LFIA), and other immunoassays targeting bPAGs.
Target Information
Target: Bovine Pregnancy-Associated Glycoproteins (bPAGs)
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