CD52 protein is a member of an unnamed short-chain GPI-anchored glycoprotein family in humans, which also includes human CD24 antigen and its homologues. CD52 protein is widely distributed and can be found on lymphocytes, monocytes, eosinophils, and dendritic cells derived from monocytes in the hematopoietic system, with a high density of up to 5×10^5 molecules per lymphocyte. In addition, CD52 antigen is also expressed to varying degrees on many lymphocytic malignancies and some acute myeloid leukemia cells. The CD52 protein may also play a role in the transport and targeting of carbohydrates, indicating that it participates in cell processes related to carbohydrate transport.
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