The AELAB P100HSP Series High Pressure Semi & Preparative HPLC systems are versatile liquid chromatography platforms designed for demanding analytical and purification tasks. Featuring reliable dual-piston parallel pump technology and compatibility with multiple detector types, these systems offer precise flow, stable pressure, and consistent separation performance across a wide range of laboratory applications.

View the product on the official AELAB website: https://aelabgroup.com/product/high-pressure-semi-preparative-types-hplc-ploohsp-series/

• Model Options:

  • Analytical (P100): 0.001–10 mL/min

  • Semi-Preparative (P100SP): 0.01–40 mL/min

  • High Pressure Semi-Prep (P100HSP): 0.01–50 mL/min

  • High Pressure Preparative (P100HP): 0.01–120 mL/min

• Max Pressure: Up to 42 MPa

• Flow Accuracy: ±1–2%

• Pump Design: Dual-piston, high-pressure binary mixer

• Pressure Fluctuation: ≤ 0.1 MPa

• Power Supply: 110V / 220V

• Refractive Index (RI100): 1.00–1.75 RIU, 7°C above ambient to 55°C

• Diode Array (DAD100): 200–900 nm, 512 arrays, 100 Hz sampling

• Evaporative Light Scattering (ELSD100): 670 nm laser diode, 0–5 mL/min, up to 110°C

• Fluorescence (FLD100): Excitation 200–890 nm, Emission 210–900 nm, 16 µL cell

• UV/UV-VIS:

  • Wavelength Range: 190–900 nm

  • Spectrum Bandwidth: 8 nm

  • Light Source: D2 / D2 + W lamp

  • Flow Cells: 6–8 µL

• Method Development: Choose P100 Analytical for precise low-flow separations in pharmaceutical labs.

• Lab-Scale Purification: Use P100SP for natural product extraction or fine chemical isolation.

• Preparative Production: P100HP suits semi-pilot scale operations in contract research or biotech firms.

• Compound isolation and purification

• Protein and peptide separation

• Analytical chemistry and pharmaceutical QC

• Environmental and food testing

• Preparative fraction collection for synthesis labs

Q: What’s the advantage of dual-piston pumps?
Dual-piston reciprocating pumps minimize pressure fluctuation and improve flow consistency for gradient and isocratic methods.

Q: Can different detectors be integrated into one system?
Yes. Compatible detectors include UV, DAD, RID, ELSD, and FLD—choose based on sensitivity and application needs.

Q: Is the system suitable for salt-containing buffers?
Absolutely. The piston rinse function and dual-seal design make it buffer-tolerant and easy to maintain.

Q: Is maintenance complex?
No. The piston seal is replaceable without opening the chassis, making upkeep simple and efficient.

Q: Can it handle semi-preparative scale purifications?
Yes. Flow rates up to 120 mL/min and pressure capacity of 42 MPa support high-volume purifications.

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