COL2A1 (collagen type II alpha 1 chain) encodes the alpha-1 chain of type II collagen, a fibrillar collagen found in cartilage and the vitreous humor of the eye. Mutations in COL2A1 are associated with achondrogenesis, chondrodysplasia, early onset familial osteoarthritis, SED congenita, Langer-Saldino achondrogenesis, Kniest dysplasia, Stickler syndrome type I, and spondyloepimetaphyseal dysplasia Strudwick type. In addition, defects in processing chondrocalcin, a calcium binding protein that is the C-propeptide of this collagen molecule, are also associated with chondrodysplasia. There are two transcripts identified for COL2A1.
The Abbkine Collagen II Mouse Mouse Monoclonal Antibody (1H1) was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen and detects endogenous Collagen II protein . The antibody has been validaed in IHC-P and reacts with Human, Mouse, Rat samples.
Abbkine supplies below price/size: $100/30μl, $220/100μl, $360/200μl of Mouse Anti-Collagen II Mouse Monoclonal Antibody (1H1) at https://www.abbkine.com/product/collagen-ii-mouse-monoclonal-antibody-1h1-abm40364.
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