The protein encoded by SMAD3 (SMAD family member 3) belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene ‘mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein functions as a transcriptional modulator activated by transforming growth factor-beta and is thought to play a role in the regulation of carcinogenesis.
The Abbkine Phospho-Smad3 (S425) Mouse Mouse Monoclonal Antibody (1D9) was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen and detects endogenous Phospho-Smad3(S425) protein. The antibody has been validaed in IHC-P and reacts with Human, Mouse, Rat samples.
Abbkine supplies below price/size: $100/30μl, $220/100μl, $360/200μl of Mouse Anti-Phospho-Smad3 (S425) Mouse Monoclonal Antibody (1D9) at https://www.abbkine.com/product/phospho-smad3-s425-mouse-monoclonal-antibody-1d9-abm40339.
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