CDH5 (cadherin 5) encodes a classical cadherin of the cadherin superfamily. The encoded preproprotein is proteolytically processed to generate the mature glycoprotein. This calcium-dependent cell-cell adhesion molecule is comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Functioning as a classical cadherin by imparting to cells the ability to adhere in a homophilic manner, this protein plays a role in endothelial adherens junction assembly and maintenance. CDH5 is located in a gene cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer.
The Abbkine VE-Cadherin Mouse Mouse Monoclonal Antibody (8E5) was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen anddetects endogenous levels of CDH5. The antibody has been validaed in IHC-P and reacts with Human, Mouse, Rat samples.
Abbkine supplies below price/size: $100/30μl, $220/100μl, $360/200μl of Mouse Anti-VE-Cadherin Mouse Monoclonal Antibody (8E5) at https://www.abbkine.com/product/ve-cadherin-mouse-monoclonal-antibody-8e5-abm40327.
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