BECN1 (beclin 1) encodes a protein that regulates autophagy, a catabolic process of degradation induced by starvation. The encoded protein is a component of the phosphatidylinositol-3-kinase (PI3K) complex which mediates vesicle-trafficking processes. This protein is thought to play a role in multiple cellular processes, including tumorigenesis, neurodegeneration and apoptosis. Alternative splicing results in multiple transcript variants.
The Abbkine Beclin-1 Mouse Mouse Monoclonal Antibody (5C5) was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen anddetects endogenous levels of BECN1. The antibody has been validaed in IHC-P and reacts with Human, Mouse, Rat samples.
Abbkine supplies below price/size: $100/30μl, $220/100μl, $360/200μl of Mouse Anti-Beclin-1 Mouse Monoclonal Antibody (5C5) at https://www.abbkine.com/product/beclin-1-mouse-monoclonal-antibody-5c5-abm40318.
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