LGALS3 (galectin 3) encodes a member of the galectin family of carbohydrate binding proteins. Members of this protein family have an affinity for beta-galactosides. The encoded protein is characterized by an N-terminal proline-rich tandem repeat domain and a single C-terminal carbohydrate recognition domain. This protein can self-associate through the N-terminal domain allowing it to bind to multivalent saccharide ligands. This protein localizes to the extracellular matrix, the cytoplasm and the nucleus. This protein plays a role in numerous cellular functions including apoptosis, innate immunity, cell adhesion and T-cell regulation. The protein exhibits antimicrobial activity against bacteria and fungi. Alternate splicing results in multiple transcript variants.
The Abbkine Galectin-3 Mouse Mouse Monoclonal Antibody (8B9) was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen anddetects endogenous levels of LGALS3. The antibody has been validaed in ELISA and reacts with Human samples.
Abbkine supplies below price/size: $100/30μl, $220/100μl, $360/200μl of Mouse Anti-Galectin-3 Mouse Monoclonal Antibody (8B9) at https://www.abbkine.com/product/galectin-3-mouse-monoclonal-antibody-8b9-abm40263.
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