The protein encoded by STAT1 (signal transducer and activator of transcription 1) is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein can be activated by various ligands including interferon-alpha, interferon-gamma, EGF, PDGF and IL6. This protein mediates the expression of a variety of genes, which is thought to be important for cell viability in response to different cell stimuli and pathogens. Two alternatively spliced transcript variants encoding distinct isoforms have been described.
The Abbkine STAT1 Mouse Mouse Monoclonal Antibody (8H11) was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen anddetects endogenous levels of STAT1. The antibody has been validaed in IHC-P and reacts with Human, Mouse, Rat samples.
Abbkine supplies below price/size: $100/30μl, $220/100μl, $360/200μl of Mouse Anti-STAT1 Mouse Monoclonal Antibody (8H11) at https://www.abbkine.com/product/stat1-mouse-monoclonal-antibody-8h11-abm40261.
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