Phosphatidylinositol 3-kinase phosphorylates the inositol ring of phosphatidylinositol at the 3-prime position. The enzyme comprises a 110 kD catalytic subunit and a regulatory subunit of either 85, 55, or 50 kD. PIK3R1 (phosphoinositide-3-kinase regulatory subunit 1) encodes the 85 kD regulatory subunit. Phosphatidylinositol 3-kinase plays an important role in the metabolic actions of insulin, and a mutation in PIK3R1 has been associated with insulin resistance. Alternative splicing of this gene results in four transcript variants encoding different isoforms.
The Abbkine PI3 Kinase P85α Mouse Monoclonal Antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen. The antibody has been validaed in WB, IHC-P and reacts with Mouse, Rat samples.
Abbkine supplies below price/size: $100/30μl, $220/100μl, $360/200μl of Mouse Anti-PI3 Kinase P85α Monoclonal Antibody at https://www.abbkine.com/product/pi3-kinase-p85α-monoclonal-antibody-abm40211.
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