TNF (tumor necrosis factor) encodes a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. This cytokine is mainly secreted by macrophages. It can bind to, and thus functions through its receptors TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. This cytokine is involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. This cytokine has been implicated in a variety of diseases, including autoimmune diseases, insulin resistance, and cancer. Knockout studies in mice also suggested the neuroprotective function of this cytokine.
The Abbkine TNF α Mouse Monoclonal Antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and detects TNF α. The antibody has been validaed in WB, IHC-P and reacts with Human, Mouse, Rat samples.
Abbkine supplies below price/size: $100/30μl, $220/100μl, $360/200μl of Mouse Anti-TNF α Monoclonal Antibody at https://www.abbkine.com/product/tnf-α-monoclonal-antibody-abm40206.
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