BIRC5 (baculoviral IAP repeat containing 5) is a member of the inhibitor of apoptosis (IAP) gene family, which encode negative regulatory proteins that prevent apoptotic cell death. IAP family members usually contain multiple baculovirus IAP repeat (BIR) domains, but BIRC5 encodes proteins with only a single BIR domain. The encoded proteins also lack a C-terminus RING finger domain. Gene expression is high during fetal development and in most tumors, yet low in adult tissues. Alternatively spliced transcript variants encoding distinct isoforms have been found for BIRC5.
The Abbkine Survivin Mouse Monoclonal Antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and detects endogenous Survivin protein. The antibody has been validaed in WB, IHC-P and reacts with Human, Rat samples.
Abbkine supplies below price/size: $100/30μl, $220/100μl, $360/200μl of Mouse Anti-Survivin Monoclonal Antibody at https://www.abbkine.com/product/survivin-monoclonal-antibody-abm40193.
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