HAO1 (hydroxyacid oxidase 1) is one of three related genes that have 2-hydroxyacid oxidase activity yet differ in encoded protein amino acid sequence, tissue expression and substrate preference. Subcellular location of the encoded protein is the peroxisome. Specifically, HAO1 is expressed primarily in liver and pancreas and the encoded protein is most active on glycolate, a two-carbon substrate. The protein is also active on 2-hydroxy fatty acids. The transcript detected at high levels in pancreas may represent an alternatively spliced form or the use of a multiple near-consensus upstream polyadenylation site.
The Abbkine HAO1 Mouse Monoclonal Antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and detects endogenous HAO1 protein. The antibody has been validaed in WB, IHC-P, IF and reacts with Mouse, Rat samples.
Abbkine supplies below price/size: $100/30μl, $220/100μl, $360/200μl of Mouse Anti-HAO1 Monoclonal Antibody at https://www.abbkine.com/product/hao1-monoclonal-antibody-abm40189.
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