GNAL encodes a stimulatory G protein alpha subunit which mediates odorant signaling in the olfactory epithelium. Guanine nucleotide-binding protein G(olf) subunit alpha couples dopamine type 1 receptors and adenosine A2A receptors and is widely expressed in the central nervous system. Mutations in GNAL have been associated with dystonia 25 and this gene is located in a susceptibility region for bipolar disorder and schizophrenia. Alternative splicing results in multiple transcript variants.
Gα olf Polyclonal Antibody detects endogenous levels of Gα olf protein.
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB: 1:500-1:2000, IHC-p: 1:100-1:300, ELISA: 1:20000. Not yet tested in other applications.
Gα olf Polyclonal Antibody product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
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