Glycogen synthase kinase-3 beta encoded by GSK3B is a serine-threonine kinase, belonging to the glycogen synthase kinase subfamily. Glycogen synthase kinase-3 beta is involved in energy metabolism, neuronal cell development, and body pattern formation. Polymorphisms in GSK3B have been implicated in modifying risk of Parkinson disease, and studies in mice show that overexpression of this gene may be relevant to the pathogenesis of Alzheimer disease. Alternatively spliced transcript variants encoding different isoforms have been found for GSK3B.
GSK3β Polyclonal Antibody detects endogenous levels of GSK3β protein.
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB: 1:500-1:2000, IHC-p: 1:100-1:300. IP: 2-5 ug/mg lysate. ELISA: 1:20000. Not yet tested in other applications.
GSK3β Polyclonal Antibody product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Find more details at http://www.abbkine.com/product/gsk3β-polyclonal-antibody-abp51488.
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