Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family.EPH receptor B1 encoded by EPHB1 is a receptor for ephrin-B family members.
The Abbkine EphB1/2 (phospho Tyr594/604) Rabbit Polyclonal Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and detects endogenous levels of EphB1/2 protein only when phosphorylated at Y594/604. The antibody has been validaed in WB , IF, ELISA and reacts with Human, Mouse, Rat samples.
Abbkine supplies below price/size: $100/30μl, $220/100μl, $360/200μl of Rabbit Anti-EphB1/2 (phospho Tyr594/604) Polyclonal Antibody at https://www.abbkine.com/product/ephb1-2-phospho-tyr594-604-polyclonal-antibody-abp50450.
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