M3 Micro LC (HPLC),SCIEX_specification/price/image

Product Detail
Company Profile

1, About M3 Micro LC

Increase your productivity to routinely analyze hundreds of compounds in hundreds of samples – day after day, year after year with the M3 MicroLC System.

2, Specifications

System Specifications	Value
Pump
Flow rate range Analytical gradient Loading gradient (-TE model)	5-50 μL/min or 20-200 μL/min (depends on model) 20-200 μL/min
Maximum pressure 10,000 psi	Maximum pressure 10,000 psi
Retention time reproducibility	< 0.5% RSD (@20 μL/min; 5-50 μL/min model)
Gradient delay volume	< 3 μL
Autosampler
Sample capacity	6 micro titer plates (96 or 384 well) 6 vial adapters for 54 x 2 ml vial
Injection volume range	2-50 μL
Injection volume precision	< 1% RSD full loop < 2% RSD partial loop
Carryover	< 0.005% (benzophenone)
Injection/auxiliary valve	6 port 6-32 thread size (1/32") port-to-port volume < 60 nL
Oven
Temperature range	+5℃ to 60℃
Inside dimensions (L x W x D)	8" x 3/4" x 5/8" (20 x 1.9 x 1.6 cm)
System
Instrument control	Controlled by SCIEX Analyst® 1.6.2 Software or higher, and TF 1.7 software or higher
Dimensions (L x W x D)	33.5" x 22.8" x 27.6" (85 cm x 58 cm x 70 cm)

3, Features

1> For research use only. Not for use in diagnostic procedures.

2> Built for Maximum Sensitivity and Throughput of Precious Samples

You have limited sample volume available and need high-throughput processing. The M3 MicroLC System has been developed for the sensitivity, ease of use, and throughput needs of biopharmaceutical development.

1) Maintain high throughput while increasing sensitivity (up to 10x improved LLOQ)

2) Use less sample, allowing for multiple analyses

3) Save up to 90% of solvents

4) Space saving: stackable on top of SCIEX Triple Quad™ and QTRAP® Systems

5) Controlled by Analyst® Software, designed to support 21 CFR Part 11 compliance

3> Sensitivity and Robustness for Bioanalysis

Sensitivity comparison of an Infliximab signature peptide. 20 uL of a 5 ng/mL Infliximab standard digest.

The M3 MicroLC offers unparalleled sensitivity for biotherapeutic development. Micro flow rates increase the sensitivity of your small sample volume analyses by up to 10x, as compared to analytical flow LC-MS. This makes the M3 MicroLC system the only choice when high sensitivity LC-MS/MS is required.

Engineered for robustness, the M3 MicroLC ensures accurate and reproducible results for peptide quantitation.

1) Proprietary Microfluidic Flow Control™ provides retention time reproducibility

2) Minimal dead volume flow paths for precise analyses

3) Autosampler dynamic load and wash (DLW) allows extremely low carryover

4) Trap-elute workflow minimizes sample contaminants in the system

4> Multiplexing for High Throughput

Maintain high throughput with the trap-elute workflow.Sample workflows for loading 20 uL of sample.

Designed for high throughput, the M3 MicroLC enables the use of trap-elute workflows. Sample is loaded onto at a high flow rate onto a trap column and then eluted for analysis at a micro flow rate. The result is up to 5x shorter run time than what can be achieved with direct inject micro flow.

1) High throughput with increased sensitivity

2) Regenerate the trap column during analysis to minimize run time

5> Complete Microflow UHPLC Solution

SCIEX offers a complete solution for your bioanalytical needs. Designed for ease of use with the SCIEX Turbo V™ source, we offer electrodes optimized for micro flow LC.

SCIEX offers MicroLC Columns in a wide range of particle sizes (2.7 µm - 5 µm), pore sizes (90Å - 300Å) and surface chemistries, including C18, C8, C4, CN, Phenyl, AQ, C18-superficially porous particles and Silane (SIL). Created specifically for fast peptide quantitation, we offer columns packed with HALO Peptide ES-C18.

Extracted Ion Chromatogram of 24 MRM transitions of tryptic peptides in a digested human plasma sample on a 0.3 x 150 mm HALO Peptide ES-C18 column. Flow rate was 10 μL/min; gradient 5- 35 % ACN in 10 min.