Rabbit Anti-beta Amyloid 1-42 Polyclonal Antibody
Size
200µl
Background
The cerebral and vascular plaques associated with Alzheimer's disease are mainly composed of Amyloid beta peptides. beta Amyloid is derived from cleavage of the Amyloid precursor protein and varies in length from 39 to 43 amino acids. beta Amyloid [1-40], beta Amyloid [1-42], and beta Amyloid [1-43] peptides result from cleavage of Amyloid precursor protein after residues 40, 42, and 43, respectively. The cleavage takes place by gamma-secretase during the last Amyloid precursor protein processing step. beta Amyloid [1-40], beta Amyloid [1-42], and beta Amyloid [1-43] peptides are major constituents of the plaques and tangles that occur in Alzheimer's disease. Beta Amyloid and peptides have been developed as tools for elucidating the biology of Alzheimer's disease.
Storage: Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide.Store at -20°C for 12 months.
Clonality: Polyclonal
Isotype: IgG
Host: Rabbit
Source: KLH conjugated synthetic peptide of human beta-Amyloid(1-42)
Reactivity: Human, Mouse, Rat
Conjugation: Unconjugated
Applications: WB(1:100-1000), FCM(1:20-100), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
Concentration: 1µg/µL
Synonyms: AAA; AD1; PN2; ABPP; APPI; CVAP; ABETA; PN-II; CTFgamma; Amyloid beta A4 protein; APP Alzheimer disease amyloid protein; Cerebral vascular amyloid peptide; PreA4; Protease, nexin-II; A4.
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