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Conotoxin IMI
Place of Origin:
France
Brand:
Smartox
Model:
0.5 mg
Supplier:
Smartox Biotech
Price:
195 €
Hits:
1199 
Updated:
6/18/2014
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    α Conotoxin IMI, α7 nAChR selective blocker α-conotoxin IMI (alpha-conotoxin IMI) has been isolated from the venom of the cone snail Conus imperialis. α-conotoxin IMI acts on postsynaptic membranes, and binds onto and inhibits nicotinic acetylcholine receptors (nAChR). α-conotoxin IMI is a selective blocker of α7 homomeric nicotinic acetylcholine receptors (IC50 ~ 200 nM). It has no effect on nAChRs composed of α2/ß2, α3/ß2, α4/ß2, α2/ß4, α3/ß4, or α4/ß4 subunits. α-conotoxins IMI acts independently of voltage value. This toxin is highly active against the neuromuscular receptor in frog. α-conotoxin IMI technical information AA sequence: Gly-Cys2-Cys3-Ser-Asp-Pro-Arg-Cys8-Ala-Trp-Arg-Cys12-NH2 Disulfide bonds: Cys2-Cys8 and Cys3-Cys12 Length (aa): 12 Formula: C52H78N20O15S4 Molecular Weight: 1352.92 Da Appearance: White lyophilized solid Solubility: water or saline buffer CAS number: [156467-85-5] Source: Synthetic Purity rate: > 95 % http://www.smartox-biotech.com/en/acetylcholine-receptor/75--conotoxinimi
    bio-equip.cn
    Smartox Biotechnology is specialized in supplying the life science research community with biological materials issued from animal's venoms. The company offers venom peptides for basic research and drug discovery solutions based on its venom collection and expertise.
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