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Conotoxin PIIIA
Place of Origin:
France
Brand:
Smartox
Model:
0.1 mg
Supplier:
Smartox Biotech
Price:
150 €
Hits:
1537 
Updated:
6/18/2014
  • Product Detail
  • Company Profile
    μ Conotoxin PIIIA, Blocker of Nav1.4 channels μ-Conotoxin PIIIA (mu-conotoxin PIIIA) has been isolated from the venom of the cone Conus purpurascens. μ-conotoxin PIIIA demonstrates a higher affinity for the mammalian muscle sodium channel Nav1.4 (IC50 ~ 44 nM) than for the CNS Nav1.2 subtype (IC50 ~ 640 nm). μ-Conotoxin PIIIA blocks more irreversibly amphibian muscle sodium channels than mammalian ones. μ-Conotoxin PIIIA technical information AA sequence: H-pGlu-Arg-Leu-Cys4-Cys5-Gly-Phe-Hyp-Lys-Ser-Cys11-Arg-Ser-Arg-Gln-Cys16-Lys-Hyp-His-Arg-Cys21-Cys22-NH2 (Disulfide bonds between Cys4-Cys16, Cys5-Cys21 and Cys11-Cys22) Length (aa): 22 Formula: C103H165N40O28S6 Molecular Weight: 2604.10 Da Appearance: White lyophilized solid Solubility: water and saline buffer CAS number: Source: Synthetic Purity rate: > 97 % See also conotoxin CnIIIC and conotoxin GIIIB. http://www.smartox-biotech.com/en/sodium-channel/97-conotoxin-piiia
    bio-equip.cn
    Smartox Biotechnology is specialized in supplying the life science research community with biological materials issued from animal's venoms. The company offers venom peptides for basic research and drug discovery solutions based on its venom collection and expertise.
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