HP-C18(2) uses a proprietary ODS bonding chemistry to a high surface area silica gel to achieve long retention
time and high loading capability. The ODS density is specially designed to achieve optimal selectivity for
both hydrophobic and hydrophilic compounds. The proprietary endcapping chemistry maximizes consumption
of silanol groups on the silica surface, and minimizes the free silanol groups to undetectable level. Such
unique bonding chemistry allows the phase to achieve high peak symmetry, even for basic compounds. HP-C18(2) phase is compatible with 100% aqueous mobile phases.
Packing
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Silica:
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Spherical, high purity (<10 ppm metals)
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Pore size:
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100 Å
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Particle size:
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3 and 5 µm
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Pore volume:
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1.1 ml/g
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Surface area:
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450 m²/g
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Phase structure:
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Special bonding density and proprietary endcapping
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% Carbon:
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17%
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Characteristic
· Specially designed ODS density bonded to highly pure silica
· Free silanol groups on silica surface is minimized to undetectable level
· High loadability
· Compatible with 100% aqueous mobile phases
· High column-to-column reproducibility
· Optimal selectivity for both hydrophobic and hydrophilic compounds
· Available for both analytical and preparative
· Suitable for separations of acidic, neutral and basic organic compounds, as well as pharmaceuticals,
peptides, peptide mapping, and others
· Recommended for separations in organic or mixed organic/aqueous mobile phases
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