Sepax HP-SCX Columns
Description
HP-SCX is a silica based mixed-mode strong cation exchange phase. The phase has a mixed
chemical structure of sulfonic acid and phenyl group. The mixed mode of strong cation-exchange
and hydrophobicity offers unique selectivity and high resolution separation for cationic/basic and
nitrogen containing compounds as well as desirable retention for a variety of weak cationic and
neutral organic compounds. The uniform polymeric bonding of HP-SCX enhances its stability under
various separation conditions.HP-SCX has expanded its applications from the traditional SCX
separation of cationic and nitrogen containing compounds to weak cationic and neutral organic
molecules. Examples include separation of analytes of amines and polyamines, such as alkaloids,
peptides, codeine, and cough and cold ingredients.
Packing
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Silica:
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Sperical, high purity (<10 ppm metals)
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|
Pore size:
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120 Å
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Particle size:
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3 and 5 µm
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Pore volume:
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1.0 ml/g
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Surface area:
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300 m²/g
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Phase structure:
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Polymeric and mixed mode
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% Carbon:
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11.0%
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Characteristic
· Highly controlled chemistry of polymeric monolayer formation and end-capping
· Mixed chemical structure of sulfonic acid and phenyl group
· Mixed-mode of ion-exchange and hydrophobic interaction enables high selectivity and
appropriate retention for a variety of compounds
· High stability and reliable lot-to-lot consistency
· pH stability: 1.5-8.0
· Suitable for separations of a complex of cationic, nitrogen containing, and neutral
compounds
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