DLK1/FA1 His Tag Protein, Cynomolgus,UA BIOSCIENCE_specification/price/image

Product Detail
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Product Specification

Species	Cynomolgus
Synonyms	Protein delta homolog 1, Pg2, Fetal antigen 1
Accession	A0A2K5TMQ6-1
Amino Acid Sequence	Ala24-Cys306 with His Tag at the C-terminus
Expression System	HEK293
Molecular Weight	33-45kDa (Reducing)
Purity	＞95% by SDS-PAGE & SEC-HPLC
Conjugation	Unconjugated
Tag	His Tag
Physical Appearance	Lyophilized Powder
Storage Buffer	PBS, PH7.4, 5% trehalose
Reconstitution	Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.
Stability & Storage	· 12 months from date of receipt, lyophilized powder stored at -20 to -80℃. · 3 months, -20 to -80℃ under sterile conditions after reconstitution. · 1 week, 2 to 8℃ under sterile conditions after reconstitution. · Please avoid repeated freeze-thaw cycles.
Reference	Sheng J, Wu D, Shang J, Fu X, Gao H, Rong J, Wang J, Hu J, Qi X. Usp11 maintained the survival of marginal zone B cells under ionizing radiation by deubiquitinating DLL1 and JAG2. Cell Death Dis. 2025 Feb 4;16(1):67.

Background

DLK-1, also known as preadipocyte factor 1 (Pref-1), is a transmembrane-secreted protein containing an epidermal growth factor (EGF)-like repeat sequence. It is expressed on the cell surface in various cancers, including hepatocellular carcinoma, and may serve as a potential target for monoclonal antibody therapy. DLK-1 regulates the growth of pioneer axons by modulating Wnt signaling. While primarily expressed as a transmembrane protein, a soluble form generated by ADAM17-mediated cleavage is active in inhibiting adipogenesis, the process by which pre-adipocytes differentiate into adipocytes.

AntBio is a biotechnology group company dedicated to serving life sciences, aiming to help scientists accelerate research and improve work efficiency. AntBio provides comprehensive and high-quality reagent tools for basic research, drug development, and diagnosis, including research grade antibodies, proteins, biochemical reagents, and assay kits. These research tools are widely used in different segments of life science research. The group company currently consists of three brands, Absin, Starter-Bio and UA-Bio.