Epiregulin Protein, Human,UA BIOSCIENCE_specification/price/image

Product Detail
Company Profile

Product Specification

Species	Human
Synonyms	Epiregulin; ER; EREG; proepiregulin;
Accession	O14944
Amino Acid Sequence	Val63-Leu108
Expression System	E.coli
Molecular Weight	6 kDa (Reducing)
Purity	>95% by SDS-PAGE.
Endotoxin	<0.1EU/μg
Conjugation	Unconjugated
Tag	No Tag
Physical Appearance	Lyophilized Powder
Storage Buffer	20mM Tris, 50mM NaCl, pH8.0
Reconstitution	Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.
Stability & Storage	·12 months from date of receipt, lyophilized powder stored at -20 to -80℃. ·3 months, -20 to -80℃ under sterile conditions after reconstitution. ·1 week, 2 to 8℃ under sterile conditions after reconstitution. ·Please avoid repeated freeze-thaw cycles.
Reference	Gene. 2006 Jan 17;366(1):2-16. Epub 2005 Dec 27.

Background

Epiregulin is a member of the epidermal growth factor (EGF) family of proteins that plays a key role in cell proliferation, differentiation, and tissue repair. In humans, epiregulin is a small, secreted protein that acts as a ligand for the epidermal growth factor receptor (EGFR) and ErbB4 receptor tyrosine kinases. Upon binding to its receptors, epiregulin activates downstream signaling pathways, such as the MAPK and PI3K/Akt pathways, leading to cellular responses such as cell growth, survival, and migration. Epiregulin is expressed in various tissues and is involved in processes such as wound healing, tissue regeneration, and cancer progression. Dysregulation of epiregulin signaling has been implicated in various diseases, including cancer.

AntBio is a biotechnology group company dedicated to serving life sciences, aiming to help scientists accelerate research and improve work efficiency. AntBio provides comprehensive and high-quality reagent tools for basic research, drug development, and diagnosis, including research grade antibodies, proteins, biochemical reagents, and assay kits. These research tools are widely used in different segments of life science research. The group company currently consists of three brands, Absin, Starter-Bio and UA-Bio.