GDF-5/BMP-14 Protein, Mouse,UA BIOSCIENCE_specification/price/image

Product Detail
Company Profile

Product Specification

Species	Mouse
Synonyms	Growth/differentiation factor 5; GDF-5; Bone morphogenetic protein 14 (BMP-14);
Accession	P43027
Amino Acid Sequence	Ala376-Arg495
Expression System	E.coli
Molecular Weight	15 kDa (Reducing)
Purity	>95% by SDS-PAGE.
Endotoxin	<0.1EU/μg
Conjugation	Unconjugated
Tag	No Tag
Physical Appearance	Lyophilized Powder
Storage Buffer	50mM HAc, pH2.9
Reconstitution	Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.
Stability & Storage	· 12 months from date of receipt, lyophilized powder stored at -20 to -80℃. · 3 months, -20 to -80℃ under sterile conditions after reconstitution. · 1 week, 2 to 8℃ under sterile conditions after reconstitution. · Please avoid repeated freeze-thaw cycles.
Reference	Nature. 1994 Apr 14;368(6472):639-43.

Background

Growth differentiation factor 5 (GDF-5), also known as bone morphogenetic protein 14 (BMP-14), is a member of the transforming growth factor beta (TGF-β) superfamily. It plays a crucial role in skeletal development and joint formation, as well as in the regulation of cell growth and differentiation. In mice, GDF-5/BMP-14 is essential for the proper development of bones, cartilage, and joints, and mutations in the GDF-5 gene have been associated with skeletal abnormalities and joint disorders. GDF-5/BMP-14 exerts its biological activities by binding to specific cell surface receptors and activating downstream signaling pathways that regulate gene expression and cellular functions involved in skeletal development and maintenance.

AntBio is a biotechnology group company dedicated to serving life sciences, aiming to help scientists accelerate research and improve work efficiency. AntBio provides comprehensive and high-quality reagent tools for basic research, drug development, and diagnosis, including research grade antibodies, proteins, biochemical reagents, and assay kits. These research tools are widely used in different segments of life science research. The group company currently consists of three brands, Absin, Starter-Bio and UA-Bio.