Cluster of Differentiation 24 (CD24) is a mucin-type glycoprotein linked to the cell membrane via glycosylphosphatidylinositol (GPI). It is expressed on the surface of B-cells. Elevated levels of CD24 expression have been observed in various epithelial cancers, including ovarian, breast, non-small cell lung, prostate, and pancreatic cancers. CD24 plays a role in molecular adhesion and the spread of metastatic tumors, and it serves as a normal receptor for P-selectin. The CD24/P-selectin interaction may be significant in the dissemination of tumor cells by facilitating their interaction with platelets and endothelial cells. Furthermore, CD24 has been considered a potential tumor marker.