CD229/SLAMF3 His Tag Protein, Mouse,UA BIOSCIENCE_specification/price/image

Product Detail
Company Profile

Product Specification

Species	Mouse
Synonyms	SLAMF3, Ly9, Ly-9
Accession	Q4VBG4
Amino Acid Sequence	Lys48-Phe454 with His Tag at C-Terminus
Expression System	HEK293
Molecular Weight	70-80kDa (Reducing)
Purity	＞95% by SDS-PAGE & ＞90% by SEC-HPLC
Conjugation	Unconjugated
Tag	His Tag
Physical Appearance	Lyophilized Powder
Storage Buffer	PBS, PH7.4, 5% trehalose
Reconstitution	Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.
Stability & Storage	· 12 months from date of receipt, lyophilized powder stored at -20 to -80℃. · 3 months, -20 to -80℃ under sterile conditions after reconstitution. · 1 week, 2 to 8℃ under sterile conditions after reconstitution. · Please avoid repeated freeze-thaw cycles.
Reference	Somuncular E, Su TY, Dumral Ö, Johansson AS, Luc S. Combination of CD49b and CD229 Reveals a Subset of Multipotent Progenitors With Short-Term Activity Within the Hematopoietic Stem Cell Compartment. Stem Cells Transl Med. 2023 Nov 3;12(11):720-726.

Background

CD229, also known as Ly9 or SLAMF3, is a 120 kDa type I transmembrane glycoprotein belonging to the SLAM subgroup within the CD2 family. This protein is prominently expressed on T and B cells, thymocytes, and to a lesser extent on NK cells. The N-terminal Ig-like domain of CD229 facilitates homophilic binding between CD229 molecules.CD229/SLAMF3 serves as an autoligand receptor within the SLAM family, playing a crucial role in the regulation of immune cell activation and differentiation. It achieves this through homotypic or heterotypic interactions, which are essential for modulating immune responses.

AntBio is a biotechnology group company dedicated to serving life sciences, aiming to help scientists accelerate research and improve work efficiency. AntBio provides comprehensive and high-quality reagent tools for basic research, drug development, and diagnosis, including research grade antibodies, proteins, biochemical reagents, and assay kits. These research tools are widely used in different segments of life science research. The group company currently consists of three brands, Absin, Starter-Bio and UA-Bio.