TPO (175aa) Protein, Mouse,UA BIOSCIENCE_specification/price/image

Product Detail
Company Profile

Product Specification

Species	Mouse
Synonyms	Thrombopoietin; C-mpl ligand (ML); Megakaryocyte colony-stimulating factor; Megakaryocyte growth and development factor (MGDF); Myeloproliferative leukemia virus oncogene ligand;
Accession	P40226
Amino Acid Sequence	Ser22-Phe196
Expression System	E.coli
Molecular Weight	18 kDa (Reducing)
Purity	>95% by SDS-PAGE.
Endotoxin	<0.1EU/μg
Conjugation	Unconjugated
Tag	No Tag
Physical Appearance	Lyophilized Powder
Storage Buffer	PBS, pH 7.4
Reconstitution	Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.
Stability & Storage	· 12 months from date of receipt, lyophilized powder stored at -20 to -80℃. · 3 months, -20 to -80℃ under sterile conditions after reconstitution. · 1 week, 2 to 8℃ under sterile conditions after reconstitution. · Please avoid repeated freeze-thaw cycles.
Reference	Annu Rev Med. 2009:60:193-206.

Background

Thrombopoietin (TPO) is a glycoprotein hormone that plays a critical role in regulating the production and maturation of platelets in the bone marrow. TPO is primarily produced in the liver and kidney and acts on hematopoietic stem cells and megakaryocytes to stimulate platelet production. TPO binds to its receptor, the thrombopoietin receptor (c-Mpl), leading to the activation of signaling pathways that promote the proliferation and differentiation of megakaryocytic progenitor cells. TPO is essential for maintaining platelet homeostasis and is involved in various physiological processes, including hemostasis, thrombopoiesis, and immune regulation.

AntBio is a biotechnology group company dedicated to serving life sciences, aiming to help scientists accelerate research and improve work efficiency. AntBio provides comprehensive and high-quality reagent tools for basic research, drug development, and diagnosis, including research grade antibodies, proteins, biochemical reagents, and assay kits. These research tools are widely used in different segments of life science research. The group company currently consists of three brands, Absin, Starter-Bio and UA-Bio.