FGF-5 Protein, Human,UA BIOSCIENCE_specification/price/image

Product Detail
Company Profile

Product Specification

Species	Human
Synonyms	Fibroblast growth factor 5; FGF-5; Heparin-binding growth factor 5 (HBGF-5); Smag-82;
Amino Acid Sequence	His21-Gly268
Expression System	E.coli
Molecular Weight	30 kDa (Reducing)
Purity	>95% by SDS-PAGE.
Endotoxin	<0.1EU/μg
Conjugation	Unconjugated
Tag	No Tag
Physical Appearance	Lyophilized Powder
Storage Buffer	20mM Tris, 500mM NaCl, 1mM DTT, pH8.0
Reconstitution	Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.
Stability & Storage	· 12 months from date of receipt, lyophilized powder stored at -20 to -80℃. · 3 months, -20 to -80℃ under sterile conditions after reconstitution. · 1 week, 2 to 8℃ under sterile conditions after reconstitution. · Please avoid repeated freeze-thaw cycles.
Reference	Proc Natl Acad Sci U S A. 2013 Dec 3;110(49):19679-88.

Background

Fibroblast Growth Factor 5 (FGF-5) is a member of the fibroblast growth factor (FGF) family, which plays a crucial role in various cellular processes, including cell proliferation, differentiation, and survival. FGF-5 is primarily known for its involvement in regulating hair growth and cycling. It is expressed in the hair follicles and acts as a negative regulator of hair follicle growth. FGF-5 signaling is essential for the transition between different phases of the hair growth cycle, including the growth phase (anagen), regression phase (catagen), and resting phase (telogen). Dysregulation of FGF-5 expression or activity has been linked to hair loss disorders, such as alopecia, highlighting its importance in hair follicle biology.

AntBio is a biotechnology group company dedicated to serving life sciences, aiming to help scientists accelerate research and improve work efficiency. AntBio provides comprehensive and high-quality reagent tools for basic research, drug development, and diagnosis, including research grade antibodies, proteins, biochemical reagents, and assay kits. These research tools are widely used in different segments of life science research. The group company currently consists of three brands, Absin, Starter-Bio and UA-Bio.