CCL17/TARC Protein, Human,UA BIOSCIENCE_specification/price/image

Product Detail
Company Profile

Product Specification

Species	Human
Synonyms	C-C motif chemokine 17; CC chemokine TARC; Small-inducible cytokine A17; Thymus and activation-regulated chemokine;
Accession	Q92583
Amino Acid Sequence	Ala24-Ser94
Expression System	E.coli
Molecular Weight	10 kDa (Reducing)
Purity	>95% by SDS-PAGE and HPLC.
Endotoxin	<0.1EU/μg
Conjugation	Unconjugated
Tag	No Tag
Physical Appearance	Lyophilized Powder
Storage Buffer	20mM PB, 500mM NaCl, pH7.4
Reconstitution	Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.
Stability & Storage	· 12 months from date of receipt, lyophilized powder stored at -20 to -80℃. · 3 months, -20 to -80℃ under sterile conditions after reconstitution. · 1 week, 2 to 8℃ under sterile conditions after reconstitution. · Please avoid repeated freeze-thaw cycles.
Reference	Int Immunol. 1999 Jan;11(1):81-8.

Background

CCL17, also known as thymus and activation-regulated chemokine (TARC), is a small cytokine belonging to the CC chemokine family. It is produced by various cell types, including dendritic cells, macrophages, and endothelial cells, and plays a crucial role in regulating immune cell migration and activation. CCL17/TARC is involved in the recruitment of T cells, particularly T helper type 2 (Th2) cells, to sites of inflammation and is implicated in the pathogenesis of allergic and inflammatory diseases, such as atopic dermatitis and asthma. CCL17/TARC binds to its receptor CCR4 and mediates chemotaxis of CCR4-expressing cells, contributing to the orchestration of immune responses.

AntBio is a biotechnology group company dedicated to serving life sciences, aiming to help scientists accelerate research and improve work efficiency. AntBio provides comprehensive and high-quality reagent tools for basic research, drug development, and diagnosis, including research grade antibodies, proteins, biochemical reagents, and assay kits. These research tools are widely used in different segments of life science research. The group company currently consists of three brands, Absin, Starter-Bio and UA-Bio.