CCL14a/HCC-1(66aa) Protein, Human,UA BIOSCIENCE_specification/price/image

Product Detail
Company Profile

Product Specification

Species	Human
Synonyms	C-C motif chemokine 14; Chemokine CC-1/CC-3 (HCC-1/HCC-3); HCC-1(1-74); NCC-2; Small-inducible cytokine A14;
Accession	Q16627
Amino Acid Sequence	Gly28-Asn93
Expression System	E.coli
Molecular Weight	7.8 kDa (Reducing)
Purity	>95% by SDS-PAGE and HPLC.
Endotoxin	<0.1EU/μg
Conjugation	Unconjugated
Tag	No Tag
Physical Appearance	Lyophilized Powder
Storage Buffer	20mM PB, 500mM NaCl, pH7.0
Reconstitution	Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.
Stability & Storage	· 12 months from date of receipt, lyophilized powder stored at -20 to -80℃. · 3 months, -20 to -80℃ under sterile conditions after reconstitution. · 1 week, 2 to 8℃ under sterile conditions after reconstitution. · Please avoid repeated freeze-thaw cycles.
Reference	BMC Genomics. 2008 May 15:9:222.

Background

CCL14a, also known as HCC-1 (Hematopoietic Cell-Derived CC Chemokine 1), is a chemokine belonging to the CC chemokine family. It is involved in immune regulation and inflammation. CCL14a/HCC-1 is produced by various cell types, including monocytes, macrophages, and dendritic cells, in response to inflammatory stimuli.
CCL14a/HCC-1 functions by binding to specific chemokine receptors on target cells, such as CCR1 and CCR5, to induce chemotaxis and activation of immune cells. It plays a role in recruiting leukocytes to sites of inflammation and modulating immune responses.
Research has shown that CCL14a/HCC-1 is implicated in various physiological and pathological processes, including immune cell trafficking, inflammatory diseases, and cancer. Understanding the role of CCL14a/HCC-1 in these processes may provide insights into potential therapeutic strategies for targeting this chemokine in the treatment of related conditions.

AntBio is a biotechnology group company dedicated to serving life sciences, aiming to help scientists accelerate research and improve work efficiency. AntBio provides comprehensive and high-quality reagent tools for basic research, drug development, and diagnosis, including research grade antibodies, proteins, biochemical reagents, and assay kits. These research tools are widely used in different segments of life science research. The group company currently consists of three brands, Absin, Starter-Bio and UA-Bio.