Fc γ RI/CD64 His Tag Protein, Mouse,UA BIOSCIENCE_specification/price/image

Product Detail
Company Profile

Product Specification

Species	Mouse
Synonyms	CD64 antigen, CD64, CD64a, Fc fragment of IgG, high affinity Ia, receptor (CD64), Fc gamma RI, FCG1, Fc-gamma receptor I B2, Fc-gamma RI, Fc-gamma RIA, FcgammaRIa, FCGR1, FcgRI, FcgRIA, FCRI, FcRIA, FLJ18345, high affinity Ia, receptor for (CD64), high affinity immunoglobulin gamma Fc receptor I, IgG Fc receptor I
Accession	P26151-1
Amino Acid Sequence	Glu25-Pro297, with C-terminal His
Expression System	HEK293
Molecular Weight	45-55kDa(Reducing)
Purity	＞95%, by SDS-PAGE under reducing conditions
Endotoxin	<0.1EU/μg
Conjugation	Unconjugated
Tag	His Tag
Physical Appearance	Lyophilized Powder
Storage Buffer	PBS, pH7.4
Reconstitution	Reconstitute at less than 1 mg/mL according to the size in ultrapure water after rapid centrifugation .
Stability & Storage	· 12 months from date of receipt, lyophilized powder stored at -20 to -80℃. · 3 months, -20 to -80℃ under sterile conditions after reconstitution. · 1 week, 2 to 8℃ under sterile conditions after reconstitution. · Please avoid repeated freeze-thaw cycles.

Background

Fc γ RI, also known as CD64, is a complete cell membrane glycoprotein, which transmits activation signals through the related Fc R γ chain, which is usually called Fc-γ RI 1 (Fc γ RI). The high affinity recognition of Fc γ RI to IgG allows it to trigger the effect response at low IgG concentration in the early immune response. After binding to IgG, CD64 interacts with an accessory chain called a common gamma chain, which has the ITAM motif necessary to trigger cells to activate. It is usually constitutively expressed on monocytes and macrophages and can be induced by neutrophils and eosinophils. Its expression is up-regulated in bacterial infections and sepsis. This product is produced by recombinant expression of mouse Fc γ RI from HEK293 cell line, which is purified, sterilized, filtered, packaged and freeze-dried.

AntBio is a biotechnology group company dedicated to serving life sciences, aiming to help scientists accelerate research and improve work efficiency. AntBio provides comprehensive and high-quality reagent tools for basic research, drug development, and diagnosis, including research grade antibodies, proteins, biochemical reagents, and assay kits. These research tools are widely used in different segments of life science research. The group company currently consists of three brands, Absin, Starter-Bio and UA-Bio.