FGF-8c Protein, Mouse,UA BIOSCIENCE_specification/price/image

Product Detail
Company Profile

Product Specification

Species	Mouse
Synonyms	FGF-8c, rMuFGF-8c, AIGF, HBGF-8
Accession	P37237
Amino Acid Sequence	Gln23-Arg268
Expression System	E.coli
Molecular Weight	28-29kDa
Purity	>95% by SDS-PAGE
Endotoxin	<1EU/μg
Conjugation	Unconjugated
Tag	No Tag
Physical Appearance	Lyophilized Powder
Storage Buffer	20mM Tris, 100mM NaCl, pH8.0
Reconstitution	Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.
Stability & Storage	12 months from date of receipt, -20 to -70 °C as supplied; 6 months, -20 to -70 °C under sterile conditions after reconstitution; 1 week, 2 to 8 °C under sterile conditions after reconstitution; Please avoid repeated freeze-thaw cycles.

Background

Fibroblast Growth Factor 8 was originally identified as an androgen-dependent growth of mouse mammary carcinoma cells. The primary transcript of mouse FGF-8 is alternatively spliced to generate at least 8 secreted isoforms that differ at their amino terminus. The differences between the isoforms exist in the number of potential N-linked glycosylation sites. In mouse, the eight isoforms are labeled as 8a through 8h. Human FGF-8 is limited to only four isoforms. Only isoforms 8a, 8b, 8e, and 8f are synthesized in humans. Mouse and human 8a and 8b isoforms are 100% identical, while the 8e and 8f isoforms are 98% identical. The FGF-8 isoforms differentially activate the various alternatively spliced forms of the FGF receptors 1-3, and FGF receptor 4. The isoform FGF-8c activates FGF R3c and FGF R4.

AntBio is a biotechnology group company dedicated to serving life sciences, aiming to help scientists accelerate research and improve work efficiency. AntBio provides comprehensive and high-quality reagent tools for basic research, drug development, and diagnosis, including research grade antibodies, proteins, biochemical reagents, and assay kits. These research tools are widely used in different segments of life science research. The group company currently consists of three brands, Absin, Starter-Bio and UA-Bio.