BTLA His Tag Protein, Mouse,UA BIOSCIENCE_specification/price/image

Product Detail
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Product Specification

Species	Mouse
Synonyms	CD272
Accession	Q32MV9
Amino Acid Sequence	Glu30-Gly176, with C-terminal 10*His
Expression System	HEK293
Molecular Weight	30-45kDa
Purity	>95% by SDS-PAGE
Endotoxin	<0.1EU/μg
Conjugation	Unconjugated
Tag	His Tag
Physical Appearance	Lyophilized Powder
Storage Buffer	PBS, pH7.4
Reconstitution	Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.
Stability & Storage	· 12 months from date of receipt, lyophilized powder stored at -20 to -80℃. · 3 months, -20 to -80℃ under sterile conditions after reconstitution. · 1 week, 2 to 8℃ under sterile conditions after reconstitution. · Please avoid repeated freeze-thaw cycles.
Reference	1. DDEL RIO ML, KAYE J, RODRIGUEZ BARBOSA JI. Detection of protein on BTLAlow cells and in vivo antibody-mediated down-modulation of BTLA on lymphoid and myeloid cells of C57BL/6 and BALB/c BTLA allelic variants.[J]. Immunobiology: Zeitschrift fur Immunitatsforschung, 2010 ,215(7):570-578.

Background

B-and T-lymphocyte attenuator (BTLA) is also known as B-and T-lymphocyte-associated protein, CD antigen CD272. BTLA is a inhibitory molecule which belongs to the Ig superfamily that attenuates BCR and TCR-mediated signaling, and thereby functions as a negative regulator of lymphocyte activation. BTLA contains one Ig-like V-type (immunoglobulin-like) domain. As a lymphocyte inhibitory receptor, BTLA / CD272 inhibits lymphocytes during immune response. BTLA is not expressed by naive T cells, but it is induced during activation and remains expressed on T helper type 1 (T(H)1) but not T(H)2 cells.

AntBio is a biotechnology group company dedicated to serving life sciences, aiming to help scientists accelerate research and improve work efficiency. AntBio provides comprehensive and high-quality reagent tools for basic research, drug development, and diagnosis, including research grade antibodies, proteins, biochemical reagents, and assay kits. These research tools are widely used in different segments of life science research. The group company currently consists of three brands, Absin, Starter-Bio and UA-Bio.