GLP1R full length Flag&His Tag Protein,Human,UA BIOSCIENCE_specification/price/image

Product Detail
Company Profile

Product Specification

Species

Human

Synonyms

GLP-1; GLP-1-R; GLP-1R

Accession

P43220

Concentration

1.08 mg/ml

Amino Acid Sequence

R24-F257, E262-K437, S193C, I196F, S225A, M233C, S271A, I317C, G318I, G361C, K346A, C347F, E387D

Expression System

Baculovirus-InsectCells

Molecular Weight

57.3KDa

Endotoxin

<1EU/μg

Conjugation

Unconjugated

Tag

His Tag, Flag Tag

Physical Appearance

Liquid

Storage Buffer

20 mM HEPES pH 7.5, 150 mM NaCl, 0.05% (w/v) GDN, 0.005% (w/v) CHS.

Stability & Storage

-80°C

Background

A 7-transmembrane protein that functions as a receptor for glucagon-like peptide 1 (GLP-1) hormone, which stimulates glucose-induced insulin secretion. This receptor, which functions at the cell surface, becomes internalized in response to GLP-1 and GLP-1 analogs, and it plays an important role in the signaling cascades leading to insulin secretion. It also displays neuroprotective effects in animal models. Polymorphisms in this gene are associated with diabetes. The protein is an important drug target for the treatment of type 2 diabetes and stroke. Alternative splicing of this gene results in multiple transcript variants.

Guidelines

For complete recovery, mix well and spin before use.
Product must not be store in diluted solutions.
Aliquots below 10l are not advisable.
Avoid repetitive freeze-thaw cycles!

AntBio is a biotechnology group company dedicated to serving life sciences, aiming to help scientists accelerate research and improve work efficiency. AntBio provides comprehensive and high-quality reagent tools for basic research, drug development, and diagnosis, including research grade antibodies, proteins, biochemical reagents, and assay kits. These research tools are widely used in different segments of life science research. The group company currently consists of three brands, Absin, Starter-Bio and UA-Bio.